Deep Tech for Human and Planetary Health
SOSV is a global, multi-stage venture capital firm that invests in deep tech startups, starting at pre-seed, and operates the deeply resourced HAX and IndieBio programs in New York, Newark and San Francisco.
We help startups go further, faster.
3
Locations
85,000
231
2021-2024
44%
2021-2024
$6.5B
2021-2024
1000+
Bruce Donald, Marcel Frenkel and Mark Hallen are analyzing over 19,290,123 compounds per second at quantum accuracies to develop drugs to previously incurable cancers.
Funded with $57 million from DCVC, Lowercarbon Capital and SOSV, among others, unspun aims to eliminate 1% of global carbon emissions
While it might look like a plant-based food company, NotCo is in the data and AI business—and aims to disrupt R&D in many industries that use animal and plant ingredients.
Miranda Wang and Jeanny Yao have an uncanny talent for finding value where others see waste. Their plastics upcycling company, Novoloop, just raised a $21m Series A to prove it.
While volunteering in a Syrian refugee camp, stem cell biologist Deniz Kent saw what climate change could do to humanity at a massively greater scale. He co-founded Prolific Machines with Max Huisman and Declan Jones to address a top source of greenhouse gas emissions: livestock.
It was 2015, and Chiu Chau was on the ropes. He had pitched nearly 150 venture capital firms. No one would invest. Everyone doubted the startup with the open-source laboratory robot.
To find the future of food, you may have to look no further than Emeryville, CA, a small city by the San Francisco Bay, where Upside Foods has built a 53,000-square-foot production facility for cultivated meat.
In a timeless dilemma for new parents, Radhika and her husband Bharath discovered early that their baby daughter was a fussy sleeper. The situation left them tired and frustrated; being effective at work became a challenge.
Gilberto Loureiro grew up inspecting fabrics in a Portuguese textile factory. With Smartex, he and co-founders Antonio Rocha and Paulo Ribeiro are eliminating textile defects—and their enormous cost both to manufacturers and the environment.
Adebayo (“Ade”) Alonge and Amy Kao, co-founders of RxAll had invented a handheld scanner for detecting counterfeit prescription drugs—an illicit, multibillion-dollar industry that kills an estimated 1 million people annually around the world and 100,000 in Africa.

First Check in Deep Tech®
With $1.5 billion in assets under management, SOSV makes 60 “first check” pre-seed investments, up to $550k, each year, as well as 150 follow-on investments. The pre-seed founders join SOSV’s industry leading HAX and IndieBio startup development programs, located in New York, Newark, and San Francisco. SOSV is the most active deep tech venture investor in the world. Is SOSV right for you?

Human & Planetary Health
SOSV’s mission is to launch founders who have the insights, vision and grit to launch incredible technology companies bound to benefit human and planetary health. That includes the vast effort to make humanity’s means of production more sustainable, from powering the grid to feeding the planet, and to make people healthier, whether addressing the toughest cancers or diagnosing the most elusive conditions. Beyond capital, SOSV produces unique, high profile events including the annual SOSV Climate Tech Summit and Deep Tech Live series to spotlight breakthrough ideas.

Built for Builders
SOSV’s HAX and IndieBio startup development programs offer 85,000 square feet of labs for bio-safety, chemical, mechatronics, analytics, and electrical engineering across facilities in New York, Newark and San Francisco. Founders work side-by-side with investment, engineering, and design teams to turn research and early prototypes into scalable, commercially exciting startups ready for further investment. Beyond the U.S., SOSV has staff in Pune, Shenzhen, and Tokyo who round out SOSV’s 24/7 global innovation engine and network of engineers, scientists, universities, corporates, and co-investors.

That Next Check Too
SOSV’s pre-seed investment is just the beginning. SOSV’s portfolio has more than 1,000 co-investors, and SOSV uses that network to help founders find investors for their series seed, series A and later stage capital. For companies completing the HAX and IndieBio programs, SOSV produces virtual and in-person demo days that reach hundreds of investors, and for founders at all stages, SOSV produces virtual VC-Founder Matchups several times a year. Between 2021 and 2024, SOSV’s portfolio companies raised $6.5 billion with SOSV participating in 579 follow on rounds..

Diverse by Design
SOSV believes that great founders come from all geographies, genders, and backgrounds. Our 900 deep tech startups include founders from 79 nationalities operating in 59 countries. 44% of founders hold PhDs and 32% of startups include at least one female founder. What all SOSV founders have in common is a drive to deliver incredible science and technology that will make the world a better place for generations to come.

SOSV for Life
The friendships founders build at SOSV’s HAX and IndieBio startup programs last forever, and so do their ties to SOSV’s general partners and expert program staff, who long remain trusted advisors. SOSV continues helping founders raise investment, expand networks, and win press coverage long after the program ends.
SOSV Programs
SOSV staff at HAX and IndieBio work with founders around the world
Not sure which program is right for your startup?
Learn more about SOSV pre-seed investment and startup development programs.
Invest with SOSV
SOSV welcomes co-investors in portfolio companies as well as limited partners in SOSV funds
Invest in our Companies
SOSV’s portfolio companies raise hundreds follow-on rounds each year, and the co-investors in SOSV’s 1000+ portfolio number in the 100s. SOSV aims to build a global, diverse network of investors, and new co-investors are always welcome.
Invest in our Funds
SOSV is a multi-stage VC that invests in 60 pre-seed startups each year and joins hundreds of follow-on rounds through SOSV’s core and select funds. New limited partners interested in “human and planetary health” are welcome.