Deep Tech for Human and Planetary Health
SOSV is the world’s most active deep tech venture capital firm investing at pre-seed, with deeply resourced locations for founders in New York, Newark, and San Francisco.
We help startups go further, faster.
7,500
800+
85,000
44%
$7.5B
2021-2025
2,700
Bruce Donald, Marcel Frenkel and Mark Hallen are analyzing over 19,290,123 compounds per second at quantum accuracies to develop drugs to previously incurable cancers.
Funded with $57 million from DCVC, Lowercarbon Capital and SOSV, among others, unspun aims to eliminate 1% of global carbon emissions
While it might look like a plant-based food company, NotCo is in the data and AI business—and aims to disrupt R&D in many industries that use animal and plant ingredients.
Miranda Wang and Jeanny Yao have an uncanny talent for finding value where others see waste. Their plastics upcycling company, Novoloop, just raised a $21m Series A to prove it.
While volunteering in a Syrian refugee camp, stem cell biologist Deniz Kent saw what climate change could do to humanity at a massively greater scale. He co-founded Prolific Machines with Max Huisman and Declan Jones to address a top source of greenhouse gas emissions: livestock.
It was 2015, and Chiu Chau was on the ropes. He had pitched nearly 150 venture capital firms. No one would invest. Everyone doubted the startup with the open-source laboratory robot.
To find the future of food, you may have to look no further than Emeryville, CA, a small city by the San Francisco Bay, where Upside Foods has built a 53,000-square-foot production facility for cultivated meat.
In a timeless dilemma for new parents, Radhika and her husband Bharath discovered early that their baby daughter was a fussy sleeper. The situation left them tired and frustrated; being effective at work became a challenge.
Gilberto Loureiro grew up inspecting fabrics in a Portuguese textile factory. With Smartex, he and co-founders Antonio Rocha and Paulo Ribeiro are eliminating textile defects—and their enormous cost both to manufacturers and the environment.
Adebayo (“Ade”) Alonge and Amy Kao, co-founders of RxAll had invented a handheld scanner for detecting counterfeit prescription drugs—an illicit, multibillion-dollar industry that kills an estimated 1 million people annually around the world and 100,000 in Africa.
First Check in Deep Tech®
Each year, SOSV makes about 60 pre-seed investments of up to $550k each, as well as another 150 follow-on investments in deep tech companies. The pre-seed founders join SOSV’s General Partner-led teams at our offices and labs in San Francisco, New York City, and Newark for intensive, customized work designed to dramatically speed up product development, commercial strategy, regulatory advances, corporate connections and fund-raising. Is SOSV right for you?
A Deep Tech Dream Team
SOSV’s ten General Partners draw on deep experience as investors, entrepreneurs, operators, scientists and engineers. They operate as three teams, one at each location, and each ready for founders across the full breadth of deep tech, from physical AI to therapeutics, energy to critical minerals. Each location also has unique strengths, such as Silicon Valley’s investor networks, New York’s corporate and healthcare ecosystem, and Newark’s embedded design engineering and prototyping. SOSV founders have access to everything.
The Best Data and Global Reach
In addition to being the the most active pre-seed deep tech investor, SOSV gathers fine-grain data on deep tech trends through regular VC-Founder Matchups, the annual Climate Tech Summit, and the Deep Tech Live series, which engage thousands of founders each year. SOSV is no less at home in Silicon Valley than the global ecosystem. Founders in the 800+ company portfolio hail from 82 countries and operate in 58. In addition to its US offices, SOSV has teams working in India, China, and the EU, and SOSV’s 2700+ co-investors span the globe.
An Infrastructure For Builders
In the past decade, SOSV raised more than $50 million in grants to build and outfit 85,000 sq feet of labs, offices and event spaces in San Francisco, New York City, and Newark. Available labs include bio-safety (BSL1 and BSL2), chemical, mechatronics, analytics, and electrical engineering, with staff experts on hand to help. Specialists in Pune, Shenzhen, and Tokyo round out SOSV’s 24/7 global innovation engine, bringing additional design, engineering, and supply chain expertise to bear.
A Focus on Follow-ons and Exits
SOSV’s pre-seed check is just the start. Investor teams work with each founder to identify the best prospects in SOSV’s vast investor network, make individual introductions, and host carefully targeted demo days and matchups. SOSV joins early stage follow-on rounds, at least through Series B. SOSV also believes founders should understand exit strategies. The unique SOSV RETVRN program, free to SOSV companies, helps founders control their destinies.
A Lifetime Cohort
The startup crucible in the labs and offices of San Francisco, New York City, and Newark yield friendships and networks that last a lifetime. SOSV’s general partners and program staff remain trusted advisors long after the founders move on. SOSV continues helping founders raise investment, expand networks, make corporate contacts, and earn press coverage. Founders participate as VIPs in VC-Founder Matchups and speak on panels at the SOSV Climate Tech Summit, expos and other events. SOSV is for life.
SOSV Programs
SOSV Staff at SOSV SF, SOSV NY, and SOSV HAX work with founders around the world.
Invest with SOSV
SOSV welcomes co-investors in portfolio companies as well as limited partners in SOSV funds
Invest in our Companies
SOSV’s portfolio companies raise hundreds follow-on rounds each year, and the co-investors in SOSV’s 1000+ portfolio number in the 100s. SOSV aims to build a global, diverse network of investors, and new co-investors are always welcome.
Invest in our Funds
SOSV is a multi-stage VC that invests in 60 pre-seed startups each year and joins hundreds of follow-on rounds through SOSV’s core and select funds. New limited partners interested in “human and planetary health” are welcome.