A question we get asked on a regular basis is: where should I incorporate? An interesting question with lots of possible different answers and solutions. There are a number of considerations with regards to incorporation:
Fundraising
Where are your Investors?
Trading
Where is your product being manufactured & sold?
Grant availability
Is there non-dilutive funding available for locating in certain areas?
Residence
Where do you live or where do you want to live, and are there visa restrictions?
Each of these will have an impact on where you incorporate. US Investors do not generally invest into entities that are incorporated outside of the US (a Delaware C-Corp would be the standard investment entity used in the US). This is due to onerous tax filing and information requirements on US citizens for off-shore investment activity.