SOSV portfolio company Cauldron was named us one of Fast Company’s Most Innovative Companies of 2026 “for lowering the costs of industrial-scale biomanufacturing.”
Cauldron is an Australia-based biomanufacturing company that aims to transform the way everyday goods are made using precision fermentation. That technique has been used for decades in pharmaceutical manufacturing, and now Cauldron Ferm, founded in 2022, is using it to produce bioproducts—everything from dairy proteins used in making cheese and ice cream to specialty chemicals that can go into sustainable aviation fuel.
Precision fermentation uses microorganisms, like yeast, that have been programmed to produce specific molecules, such as proteins, enzymes, or peptides. In 2025, Cauldron Ferm demonstrated its hyper-fermentation technology by completing its first continuous campaign with a precision fermented protein at 10,000-liter scale, producing more volume at lower cost than conventional batch-fed systems.
Over the past year, Cauldron Ferm has onboarded six new clients, ranging from startups to multinationals. It has also received notable government, including backing from Australian officials for an industrial facility in Mackay, Queensland, and a $1.76 million award from the U.S. Department of Defense to plan a commercial-scale facility in the United States.
This recognition is a strong signal that what they’re building and how they’re building it is moving the needle for the bioeconomy. 🚀