IndieBio’s cultured meat startup Prolific Machines has emerged from stealth mode, announcing  $42M in combined seed and series A funding. Prolific Machines started in SOSV’s IndieBio development program, and Arvind Gupta at Mayfield (previously co-founder of IndieBio) led the $3.1M seed round, followed by the series A led by Breakthrough Energy Ventures.  TechCrunch described how […]

Months ago, we wrote about how Prolific Machines, one of IndieBio’s fastest-growing startups and the record-holder for fastest seed round in IndieBio history—has the key to cell cultured meat via its unique optogenetic approach. We still believe it (along with the technology’s potential for other applications in food and medicine), and tons of leading investors […]

SOSV portfolio company Prolific Machines recently spoke to FiercePharma following a big milestorne for its photomolecular platform, which uses light and optogenetics to “directly and dynamically” manipulate gene expression in living cells. The company announced it has achieved 21 g/L productivity over 15 days in an intensified fed-batch Chinese hamster ovary (CHO) cell line run […]

Lithium-ion batteries are technologically difficult and expensive to recycle—which is why 95% of batteries end up in a landfill and new battery production depends on environmentally costly lithium mining. Green Li-ion (HAX 2020) has pioneered a solution, and just raised fresh capital to expand its delivery to customers around the globe. The Singapore-based provider of […]

SOSV portfolio company unspun is taking a bold step toward reshaping how clothes are made in the U.S. The company, known for its near-zero-waste weaving technology, is planning to raise $40 million in project-level financing to build 10 factories across the U.S. These facilities will use AI-enabled 3D weaving machines designed to produce garments closer […]

SOSV announced the close of its $306 million SOSV V fund, the firm’s largest fund to date. The news received coverage in TechCrunch, Bloomberg and Axios. The text below is from the press release SOSV issued on April 16th concerning the new fund. SOSV V will focus on deep tech startups in human and planetary health, […]

Green Li-ion (HAX) secured funding from Twin Towers Ventures, the VC arm of Malaysian oil company Petronas, to help build out its Oklahoma factory. Per Axios, which exclusively covered the news, Green Li-ion “plans to raise a Series B round of $50 to $80M in the first quarter of next year. The funding rounds will […]

In the Sourcing Journal’s 2025 Material Innovation Report, Sabriya Stukes, partner at SOSV and chief scientific officer at IndieBio, weighs in on the growing urgency and opportunity around sustainable materials. She discusses the environmental toll of fashion, the return of VC interest in biomaterials, and why SOSV backs both new materials and the tools that […]

Finding the correct enzyme can be like searching for a needle in a haystack. Allozymes employs a proprietary microfluidics technology to build the next generation enzyme engineering platform. Its platform can build and test millions of enzymes per day, boosting the likelihood of success by 200x in developing the most effective enzymes. The company is […]

While energy emissions may be the biggest piece of the GHG pie, industries like food and fashion continue to contribute heavily and have costly environmental impacts as well. In its current state, the global fashion industry is wasteful and emissions-heavy—an estimated 4 percent of greenhouse gas emissions and 4 percent of global waste are attributed […]